Usually there is a small lump or series of lumps and pits in the palm of those who have Dupuytren's contracture. A cord may develop over time and run from the palm to one or more fingers, most likely the ring or middle fingers. The cords look like tendons, but are actually between the tendons and the skin. Many times both hands show the symptoms, but not in an identical manner.
The nodules that show up first may cause a little discomfort when they form, but Dupuytren's contracture isn't usually a painful condition. The first symptom of the disease relates to difficulty with laying the hand down flat on a firm surface. Once the fingers start curling toward the palm, it may become difficult to wash your hands, wear gloves, put your hands in your pockets, or even shake hands with someone. Some people who suffer from Dupuytren's disease might only have small lumps or cords while others can have fingers that are very bent. The more drastic symptoms normally show up if the disease starts earlier in life.